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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKCD All Species: 8.48
Human Site: S307 Identified Species: 14.36
UniProt: Q05655 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05655 NP_006245.2 676 77505 S307 R R S D S A S S E P V G I Y Q
Chimpanzee Pan troglodytes XP_001147999 706 81847 I310 C L R D T E Q I F R E G P V E
Rhesus Macaque Macaca mulatta XP_001083320 1140 127261 S771 R R S D S A S S E P V G I Y Q
Dog Lupus familis XP_849292 706 81555 I310 C L R D T E H I F R E G P V E
Cat Felis silvestris
Mouse Mus musculus P28867 674 77529 T305 S S R K L D T T E S V G I Y Q
Rat Rattus norvegicus P09215 673 77502 P305 A S R K P E T P E T V G I Y Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509836 708 81415 L331 T K P G T T L L P L P I P T A
Chicken Gallus gallus NP_001006133 699 80179 V305 R R S D S G S V E N V G I Y Q
Frog Xenopus laevis NP_001084460 683 78181 L306 T R K S D S G L D N I A I Y Q
Zebra Danio Brachydanio rerio Q90XF2 588 67303 G242 G K A V S S L G L I D F D L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P83099 671 76314 T293 E A R D S P S T P P S L N P A
Honey Bee Apis mellifera XP_394743 624 71014 D252 R G S T F I Y D F H V A V I N
Nematode Worm Caenorhab. elegans P34722 704 80280 N333 K N N G S L P N K L K N L F K
Sea Urchin Strong. purpuratus XP_787505 585 66691 G245 P L W T T D G G P P D R P V A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.7 58.5 63.5 N.A. 90.3 89.5 N.A. 63.7 82.4 81.4 33.2 N.A. 46.7 45.2 47.1 49.1
Protein Similarity: 100 76.7 59 77.6 N.A. 95.4 95.2 N.A. 77.9 89.9 89.5 50.8 N.A. 61.9 61.3 64.7 63.6
P-Site Identity: 100 13.3 100 13.3 N.A. 40 40 N.A. 0 80 26.6 6.6 N.A. 26.6 20 6.6 6.6
P-Site Similarity: 100 26.6 100 26.6 N.A. 53.3 46.6 N.A. 13.3 80 46.6 26.6 N.A. 33.3 26.6 53.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 0 15 0 0 0 0 0 15 0 0 22 % A
% Cys: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 43 8 15 0 8 8 0 15 0 8 0 0 % D
% Glu: 8 0 0 0 0 22 0 0 36 0 15 0 0 0 15 % E
% Phe: 0 0 0 0 8 0 0 0 22 0 0 8 0 8 0 % F
% Gly: 8 8 0 15 0 8 15 15 0 0 0 50 0 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 15 0 8 8 8 43 8 0 % I
% Lys: 8 15 8 15 0 0 0 0 8 0 8 0 0 0 8 % K
% Leu: 0 22 0 0 8 8 15 15 8 15 0 8 8 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 0 0 0 0 8 0 15 0 8 8 0 8 % N
% Pro: 8 0 8 0 8 8 8 8 22 29 8 0 29 8 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 43 % Q
% Arg: 29 29 36 0 0 0 0 0 0 15 0 8 0 0 0 % R
% Ser: 8 15 29 8 43 15 29 15 0 8 8 0 0 0 0 % S
% Thr: 15 0 0 15 29 8 15 15 0 8 0 0 0 8 0 % T
% Val: 0 0 0 8 0 0 0 8 0 0 43 0 8 22 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 43 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _